Under what circumstances can a pharmacist in Colorado refuse to fill a prescription?

A pharmacist in Colorado has the authority to refuse to fill a prescription if they suspect that it may be illegitimate or unsafe. This stems from the pharmacist's responsibility to ensure patient safety and the integrity of the medication distribution system. If a pharmacist has concerns about the validity of a prescription—such as signs of misuse, abuse, or potential harm from the medication—they are ethically and legally obligated to decline to fill the prescription. This action helps prevent potential adverse outcomes and contributes to overall public health efforts.

The other options do not align with the professional standards and legal requirements that govern pharmacy practice. Deciding not to fill a prescription based solely on the patient's ability to pay does not address safety or legal considerations. Similarly, a pharmacist is not required to contact the physician to validate a prescription before determining its legitimacy. Lastly, being too busy to fill a prescription does not constitute a valid reason to refuse service, as pharmacists must prioritize patient care and manage their time and resources effectively to fulfill their professional obligations.